Novel therapeutic approaches in Repeat expansion Disorders

In the recent years, the underlying mutations for some acquired neurodegenerative diseases have been identified. One continuous sort of change is trinucleotide repeat expansion. It is otherwise called trinucleotide repeat expansion disorder or trinucleotide repeats disorder and is a set of genetic disorder caused by an expansion in the quantity of trinucleotide repeats in specific genes. Each gene influenced by trinucleotide repeat expansion has a different number of repeats those results in sign of sickness. Further understanding of the role of inflammation in the pathogenesis of TREDs may allow for the design of better therapeutic approaches, slowing disease progression and improving the life of patients.

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